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JAK2 Inhibitor V

CAS No. 195371-52-9

JAK2 Inhibitor V ( NSC 42834; Janus-Associated Kinase Inhibitor V )

产品货号. M18188 CAS No. 195371-52-9

NSC 42834(JAK2 Inhibitor V, Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥267 有现货
5MG ¥421 有现货
10MG ¥624 有现货
25MG ¥1288 有现货
50MG ¥2333 有现货
100MG ¥4301 有现货
500MG ¥9558 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    JAK2 Inhibitor V
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NSC 42834(JAK2 Inhibitor V, Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.
  • 产品描述
    NSC 42834, also known as JAK2 Inhibitor V, is an inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 μM.
  • 同义词
    NSC 42834; Janus-Associated Kinase Inhibitor V
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    JAK2; JAK2 (V617F)
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    195371-52-9
  • 分子量
    344.45
  • 分子式
    C23H24N2O
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 43 mg/mL; 124.84 mM
  • SMILES
    O=C(C(CCc1ccccn1)(CCc1ccccn1)C)c1ccccc1
  • 化学全称
    2-methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Jacqueline Sayyah, et al. Mol Y Ther 2008;7(8):2308-18.
产品手册
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